| 产品详情 |
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| Antigenic Specificity | BAG6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAG6 Polyclonal Antibody. BAT3 (HLA-B associated transcript 3), also known as G3, scythe, BAG6 or D6S52E, is a proline-rich nuclear protein with an important role as an apoptotic regulator. BAT3 contains one ubiquitin-like domain at its N-terminus and two nuclear localization signals at its C-terminus. Specifically, BAT3 interacts with and stabilizes AIF (apoptosis inducing factor), thereby sensitizing the cell to apoptosis mediated by endoplasmic reticulum (ER) stress. Upon ricin treatment, BAT3 is cleaved by caspase-3 and its C-terminal fragment displays pro-apoptotic activities. The apoptotic activities executed include nuclear condensation, phosphatidlyserine externalization, cell rounding and shrinkage. Mice that are deficient in BAT3 |
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| Immunogen | n/a |
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| Other Names | BAG 6; BAG family molecular chaperone regulator 6; BAG-6; Bag6; BAG6_HUMAN; BAT 3; BAT3; BCL2-associated athanogene 6; D17H6S52E; D6S52E; G3; HLA B associated transcript 3; HLA-B associated transcript 3; HLA-B associated transcript-3; HLA-B-associated transcript 3; large proline rich protein BAG6; Large proline rich protein BAT3; Large proline-rich protein BAG6; large proline-rich protein BAT3; Protein G3; Protein Scythe; Scythe; Scythe, homolog of Xenopus; |
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| Gene, Accession # | Entrez: 224727, 7917, 94342; Uniprot: P46379, Q6MG49, Q9Z1R2 |
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| Catalog # | PA5-76777 |
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| Price | |
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| Order / More Info | BAG6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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