产品详情 |
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Product Name | Suppressor of Cytokine Signaling 7 (SOCS7) peptide |
Description | SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
Other Names | GB13951|zgc:175115|SOCS4|SOCS7|socs7|3110032M18Rik|A730004F22Rik|AI427843|AU015727|AU015859|Socs7|NAP4|NCKAP4|2310063P06Rik|C85125|Nap4 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN940239 |
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Order / More Info | Suppressor of Cytokine Signaling 7 (SOCS7) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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