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| Product Name | Pam3CSK4, TLR1 and TLR2 Ligand |
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| Description | Pam3CSK4, TLR1 and TLR2 Ligand is a synthetic tripalmitoylated lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein. It activates monocytes and macrophages and is also a potent activator of proinflammatory transcription factor NF-kB. Pam3CSK4, TLR1 and TLR2 Ligand is recognized by a heterodimer formed between TLR1 and TLR2.Pam3CSK4, TLR1 and TLR2 Ligand stimulation: If your cell line does not naturally express TLR1+ TLR2, co-transfect with plasmids pCMV/TLR1and pCMV/TLR2. Forty-eight hrs after transfection, stimulate cells with 10 to 100 ng/ml of Pam3CSK4 for 6-24 hrs. Determine Pam3CSK4 stimulation using appropriate detection assays. |
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| Size | 0.025 mg |
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| Concentration | 1.0 mg/ml |
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| Applications | Functional, In vitro assay, In vivo assay, Ligand Activation |
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| Other Names | Pam3CSK4, Pam3CSK4 TLR1 and TLR2 Ligand, TLR1 and TLR2 Ligand |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | NBP2-25297-0.025mg |
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| Order / More Info | Pam3CSK4, TLR1 and TLR2 Ligand from NOVUS BIOLOGICALS, LLC |
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| Product Specific References | PubMed: 21775685, 21908266, 22665377, 23403223, 23944933, 24105263, 25004110, 25511699, 25856589, 25957979, 26021803, 27123851, 27157550, 27256622, 27351455, 27431529, 28558791, 29363546, 30476082 |
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