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Product Name | Tumor Necrosis Factor (TNF) protein |
Description | Recombinant Rabbit Tumor Necrosis Factor α/TNF-α is a non-glycosylated cytokine produced from E. coli using rDNA technology. The protein consists of three identical polypeptide chains of 158 AAs combined to form a compact, bell-shaped homotrimer. The individual subunits have a relative molecular mass each of 17.4 Daltons. Tumor necrosis factor α (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | TNF|tnf|dif|tnfa|xtnf|TNF-a|tnfsf2|tnf-alpha|TNF-alpha|DIF|TNFA|TNFSF2|TNFalpha|Tnfa|Tnfsf1a|RATTNF|TNFa|cTNF|TNF-ALPHA|Cachectin|Tnf-alpha|tnfa-like |
Gene, Accession, CAS # | Gene ID: 100009088 |
Catalog # | ABIN1097667 |
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Order / More Info | Tumor Necrosis Factor (TNF) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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