| 产品详情 |
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| Antigenic Specificity | Annexin A1 (ANXA1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology. Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation. Phosphorylation by PKC, EGFR, and Chak1 results in inhibition of annexin A1 function. Annexin A1 has also been identified as one of the eat-me signals on apoptotic cells that are to be recognized and ingested by phagocytes. Annexin A1, as an endogenous anti-inflammatory mediator, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development.Synonyms: ANXA1, ANX1, LPC1 |
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| Immunogen | Recombinant protein of human ANXA1 |
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| Other Names | anx1a|anxa1|wu:fa01d11|wu:fa05d11|wu:fk69h01|MGC64363|anx1|lpc1|MGC89164|ANXA1|ANX1|LPC1|p35|Anx-1|Anx-A1|C430014K04Rik|Lpc-1|Lpc1|Anx1 |
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| Gene, Accession # | Gene ID: 301,16952,25380 |
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| Catalog # | ABIN1512576 |
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| Price | |
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| Order / More Info | Annexin A1 (ANXA1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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