产品详情 |
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Antigenic Specificity | Annexin A1 (ANXA1) |
Clone | 5E4-D8-F12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. Subunit structure: Homodimer in placenta (20% ), linked by transglutamylation. Interacts with DYSF (By similarity). Subcellular location: Nucleus. Cytoplasm. Cell projection?cilium. Basolateral cell membraneSequence similarities: Belongs to the annexin family. Contains 4 annexin repeats. |
Immunogen | Purified recombinant human Annexin A1 beta protein fragments expressed in E.coli. |
Other Names | anx1a|anxa1|wu:fa01d11|wu:fa05d11|wu:fk69h01|MGC64363|anx1|lpc1|MGC89164|ANXA1|ANX1|LPC1|p35|Anx-1|Anx-A1|C430014K04Rik|Lpc-1|Lpc1|Anx1 |
Gene, Accession # | Gene ID: 301 |
Catalog # | ABIN2169477 |
Price | |
Order / More Info | Annexin A1 (ANXA1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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