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Product Name | Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) peptide |
Description | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
Other Names | wu:fb38a06|wu:fc34f08|wu:fc49f02|PSMD12|rpn5|Rpn5|p55|1500002F15Rik|AI480719|P55 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN940128 |
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Order / More Info | Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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