| 产品详情 |
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| Product Name | DMOG |
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| Description | Purity >98%. The pro-angiogenic factor HIF-1Alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-1Alpha prolyl hydroxylase (HIF-PH). DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1Alpha expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM. DMOG is therefore expected to act as a pro-angiogenic compound, acting via the HIF-1Alpha system. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(methoxyoxoacetyl)-glycine, methyl ester, Dimethyloxallyl Glycine |
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| Gene, Accession, CAS # | CAS: 89464-63-1 |
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| Catalog # | LS-H7508 |
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| Price | |
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| Order / More Info | DMOG from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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