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| Product Name | Non-POU Domain Containing, Octamer-Binding (NONO) peptide |
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| Description | NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | NMT55|NRB54|P54|P54NRB|nmt55|nrb54|p54nrb|xp54nrb|AA407051|AV149256|nonA |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN939996 |
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| Price | |
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| Order / More Info | Non-POU Domain Containing, Octamer-Binding (NONO) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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