产品详情 |
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Antigenic Specificity | PSMB5 |
Clone | 23020 |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | IgG |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human PSMB5 monoclonal antibody for WB. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 5693, UniProt: P28074 |
Catalog # | CABT-B8952 |
Price | |
Order / More Info | PSMB5 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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