| 产品详情 |
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| Antigenic Specificity | beta-Site APP-Cleaving Enzyme 1 (BACE) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The current understanding of the role of amyloid in Alzheimer's disease (AD) has been established by a remarkable congruence of multiple disciplines: neuropathology, biochemistry, molecular biology, and epidemiological genetics. It is known that amyloid beta is derived, by two sequential cleavages, from the receptor-like amyloid precursor protein (APP). The proteases involved are beta-secretase, identified as the novel aspartyl protease BACE, and gamma-secretase, a multimeric complex containing the presenilins (PS1, PS2). BACE1 and BACE2 have been isolated as homologues of BACE. Description: Serum. Synonyms: Polyclonal BACE antibody, Anti-BACE antibody, beta Amyloid Cleaving Enzyme antibody, beta secretase antibody, BACE C-terminus antibody, APP beta-secretase antibody, asp2 antibody, aspartylprotease 2 antibody, b-Secretase antibody, bace antibody, bace1 antibody, beta-secretase antibody, beta-site amyloid precursor protein cleaving enzyme antibody, beta-site app cleaving enzyme antibody. |
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| Immunogen | BACE1 antibody was raised in rabbit using a synthetic peptide of part of human BACE1 (RLPRETDEEPEEPGRR) as the immunogenSerum |
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| Other Names | BACE1|MGC145931|bace2|MGC68881|MGC68482|BACE2|C76936|Bace|ASP2|BACE|HSPC104|zgc:77409 |
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| Gene, Accession # | Gene ID: 23621 |
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| Catalog # | ABIN927103 |
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| Order / More Info | beta-Site APP-Cleaving Enzyme 1 (BACE) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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