产品详情 |
Edit |   |
Antigenic Specificity | bACE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB, FCM. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by bACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. This BACE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the Central region of human BACE2. |
Immunogen | Human BACE2. |
Other Names | ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1,; BACE2; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Beta-site amyloid precursor protein cleaving enzyme 2; Down region aspartic protease; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; Asp 1; Beta-site APP cleaving enzyme 2; UNQ418/PRO852 |
Gene, Accession # | SwissProt: Q9Y5Z0 |
Catalog # | abx032689 |
Price | |
Order / More Info | bACE2 Antibody from ABBEXA |
Product Specific References | n/a |
产品资料 |
|
|