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| Product Name | NAE1, 1-534aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl. NAE1 (NEDD8-activating enzyme E1 regulatory subunit) belongs to the ubiquitin-activating E1 family. This protein binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. NAE1 participates in a novel ubiquitinylation-related pathway involving the ubiquitin-like molecule NEDD8. Also, this protein is required for cell cycle progression through the S/M checkpoint. Recombinant human NAE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | NEDD8 activating enzyme E1 subunit 1, A-116A10.1, APPBP1, HPP1, ula-1 |
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| Gene, Accession, CAS # | NP 003896 |
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| Catalog # | ATGP1355 |
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| Order / More Info | NAE1, 1-534aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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