产品详情 |
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Antigenic Specificity | FoXp3 |
Clone | 236A/E7 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | affinity purified |
Size | 100 ug, 500 ug |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal antibody to FoXp3. The 236A/E7 antibody reacts with human FoXp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2. FoXp3, a 49-55 kDa protein, is a member of the forkhead/winged-heliX family of transcriptional regulators, and was identified as the gene defective in scurfy (sf) mice. Constitutive high eXpression of FoXp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic eXpression of FoXp3 in CD4+CD25-cells imparts a Treg phenotype in these cells. Intracellular staining and flow cytometric analysis of freshly isolated human peripheral blood mononuclear cells (PBMCs) with the 236A/E7 antibody using the FoXp3/Transcription Factor Staining Buffer Set and protocol reveals staining of the CD4+CD25bright population. This antibody has also been shown to recognize rhesus macaque, sooty mangabey and cynomolgus macaque |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | orb158852 |
Price | |
Order / More Info | FoXp3 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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