产品详情 |
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Antigenic Specificity | GAD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB, IHC, IF/ICC. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2. |
Immunogen | Human GAD2. |
Other Names | 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform; Gad65; Gad2; Glutamate decarboxylase 2; Glutamate Decarboxylase-2 (Pancreas); Acid |
Gene, Accession # | SwissProt: Q05329 |
Catalog # | abx026096 |
Price | |
Order / More Info | GAD2 Antibody from ABBEXA |
Product Specific References | n/a |
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