| 产品详情 |
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| Antigenic Specificity | GAD2 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. This antibody is supplied as crude ascites. This GAD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from human GAD2. |
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| Immunogen | Human GAD2. |
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| Other Names | 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform; Gad65; Gad2; Glutamate decarboxylase 2; Glutamate Decarboxylase-2 (Pancreas); Acid |
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| Gene, Accession # | SwissProt: Q05329 |
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| Catalog # | abx025417 |
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| Price | |
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| Order / More Info | GAD2 Antibody from ABBEXA |
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| Product Specific References | n/a |
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