产品详情 |
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Antigenic Specificity | CTLA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CTLA4 Antibody is a Rabbit Polyclonal antibody against CTLA4. This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]. |
Immunogen | A synthetic peptide of human AKT1. |
Other Names | CTLA4; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; ICOS; IDDM12 |
Gene, Accession # | CTLA4, Gene ID: 1493, SwissProt: P16410 |
Catalog # | abx001680 |
Price | |
Order / More Info | CTLA4 Antibody from ABBEXA |
Product Specific References | n/a |
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