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| Product Name | Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 52.7kDa. Extracellular Domain: 19-238aa. C-terminal FC-tagged. Homo sapiens (Human). Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response. The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | B7 homolog 1 (B7-H1) (CD274) (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7H1) (PDCD1L1) (PDCD1LG1) (PDL1) |
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| Gene, Accession, CAS # | CD274, UniProt: Q9NZQ7 |
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| Catalog # | RPC26433 |
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| Price | |
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| Order / More Info | Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial from BIOMATIK |
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| Product Specific References | n/a |
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