| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Mouse CD8 |
|---|
| Clone | 53.6.72(lyt2) |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a |
|---|
| Format | purified |
|---|
| Size | 100µg/50µg |
|---|
| Concentration | n/a |
|---|
| Applications | FACS |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD8 exists in two forms: a CD8 heterodimer composed of a a chain and a b chain; and a homodimer of two a chains (CD8a = Lyt2, Ly2, OX8). The heterodimer is found on essentially all thymocytes and the ``suppressor/cytotoxic'' subpopulation of mature T lymphocytes. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC-Class I-restricted CD8+ T cells. CD8 is required for the development of cytotoxic T cells.(Ledbetter JA et al, 1979, Nat. Rev. Immunol., 47, 63: 425-30; Nakauchi H et al, 1995, PNAS 85, 5126-5130) |
|---|
| Immunogen | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | DDX0091 |
|---|
| Price | |
|---|
| Order / More Info | Mouse CD8 Antibody from DENDRITICS SAS |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|