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| Product Name | Cyclosporine |
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| Description | MW: 1202.63. Cyclosporin A is a hydrophobic cyclic peptide, and is a potent immune-suppressant and antifungal. It acts via its ability to bind to a family of intracellular proteins (1). The immunosuppressant action is mediated by the complex Cyclosporin-A-cyclophilin that specifically inhibits the Ca2+/calmodulin-dependent serine-threonine-protein phosphatase-2B. This is turn inhibits calcineurin and promotes dephosphorylation of transcription factor NF-AT and T-cell activation (2). |
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| Size | 25 mg, 100 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,3 1-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; Cyclosporin A |
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| Gene, Accession, CAS # | CAS: 59865-13-3 |
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| Catalog # | abx076775 |
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| Order / More Info | Cyclosporine from ABBEXA |
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| Product Specific References | n/a |
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