| 产品详情 |
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| Antigenic Specificity | PTPN5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | STEP (Protein-tyrosine phosphatase striatum-enriched) is a neural-specific protein-tyrosine phosphatase. It is also known as PTPN5 (tyrosine-protein phosphatase, non-receptor type 5). STEP immunoreactive areas are most intense in the regions of the CNS receiving a dopaminergic input (e.g. striatum, basal ganglia). STEP is part of the NMDA receptor (R) complex and inhibits NMDAR single-channel activity and NMDAR-mediated synaptic current. Phosphorylation of STEP, via D1 and PKA activation by dopamine, decreases the activity of STEP by reducing its affinity for substrate. This PTPN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PTPN5. |
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| Immunogen | Human PTPN5. |
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| Other Names | Neural-Specific Protein-Tyrosine Phosphatase; Striatum-Enriched Protein-Tyrosine Phosphatase; Step; Ptpn5; protein tyrosine phosphatase; non-receptor type 5 (striatum-enriched); FLJ14427; PTPSTEP; Tyrosine-protein phosphatase non-receptor type 5 |
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| Gene, Accession # | SwissProt: P54829 |
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| Catalog # | abx029236 |
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| Price | |
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| Order / More Info | PTPN5 Antibody from ABBEXA |
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| Product Specific References | n/a |
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