| 产品详情 |
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| Antigenic Specificity | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD40 Ligand (CD40L), a member of the TNF superfamily of ligands, is expressed as either a membrane-bound or soluble homotrimer . Both membrane-bound and soluble forms of CD40L have biological activity . CD40L is expressed primarily on activated T cells, however, mast cells, basophils, and NK cells may also express CD40L . CD40L functions as an important T cell co-stimulatory molecule and enhances T-dependent B cell responses . CD40L binds CD40, which is a receptor expressed on B cells, dendritic cells, and macrophages . Binding of CD40L to CD40 leads to the recruitment of TRAF proteins (TRAFs 2,3,5, and 6) resulting in the activation of the JNK and NF-kappaB pathways . Synonyms: CD40,Bp50,CDW40,MGC9013,TNFRSF5,p50 , |
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| Immunogen | C term -peptide of human CD40 |
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| Other Names | AI326936|Bp50|GP39|HIGM1|IGM|IMD3|T-BAM|TRAP|Tnfrsf5|p50|CDW40|TNFRSF5|TNFSF5|2310042E05Rik|C130077D06Rik|C87049|DCTN-50|GMP23-48K|RBP50 |
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| Gene, Accession # | Gene ID: 958,21939,171369 |
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| Catalog # | ABIN1683454 |
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| Order / More Info | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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