| 产品详情 |
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| Antigenic Specificity | TRAF1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRAF1 Antibody is a Rabbit Polyclonal antibody against TRAF1. TRAF1 is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. TRAF1 and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. TRAF1 is observed at 45-50 kDa in western blotting, and the additional bands of lower molecular weight (~30 kDa) may represent TRAF1 cleavage fragments, similar to the results obtained by the article (PMID:11098060). |
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| Immunogen | Recombinant protein of human TRAF1. |
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| Other Names | EBI6; MGC:10353; Tnf receptor associated factor 1; TNF receptor-associated factor 1; TRAF 1; TRAF1; Epstein-Barr Virus-Induced Protein 6; Epstein-Bar Virus-Induced Protein 6 |
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| Gene, Accession # | TRAF1, Gene ID: 7185, SwissProt: Q13077 |
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| Catalog # | abx000575 |
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| Price | |
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| Order / More Info | TRAF1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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