| 产品详情 |
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| Antigenic Specificity | TICAM1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. This TICAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the N-terminal region of human TICAM1. |
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| Immunogen | Human TICAM1. |
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| Other Names | TICAM1; PRVTIRB; TRIF; TIR domain-containing adapter molecule 1; Proline-rich; vinculin and TIR domain-containing protein B; Putative NF-kappa-B-activating protein 502H; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; TICAM-1 |
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| Gene, Accession # | TICAM1, Accession: NP_891549.1, SwissProt: Q8IUC6 |
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| Catalog # | abx034891 |
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| Price | |
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| Order / More Info | TICAM1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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