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| Antigenic Specificity | TNF alpha |
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| Clone | 6C10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 κ |
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| Format | ammonium sulfate precipitate |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNF alpha (6C10) Monoclonal Antibody. • Target Background: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation |
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| Immunogen | Recombinant human protein purified from E.coli(GFP-TNF-alpha) |
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| Other Names | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; Tumor necrosis factor; Cachectin; Tumor necrosis factor ligand superfamily member 2; TNF-a; TNF |
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| Gene, Accession # | Gene ID: 7124, SwissProt: P01375 |
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| Catalog # | bsm-50267M |
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| Price | |
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| Order / More Info | TNF alpha Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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