| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | KEAP1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | Cy5 conjugate |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | IF(IHC-P) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | KEAP1 Polyclonal Antibody, Cy5 Conjugated. • Target Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. |
|---|
| Immunogen | KLH conjugated synthetic peptide derived from human KEAP1. Immunogen Range: 75-125/624 |
|---|
| Other Names | INrf2; KLHL19; Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; Kelch-like protein 19; KEAP1; KIAA0132 |
|---|
| Gene, Accession # | Gene ID: 9817, SwissProt: Q14145 |
|---|
| Catalog # | bs-3648R-Cy5 |
|---|
| Price | |
|---|
| Order / More Info | KEAP1 Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|