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Antigenic Specificity | Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The aldehyde dehydrogenase family is a large group of enzymes that oxidize aldehydes formed through metabolic processes to their carboxylic acids . ALDH1A1 is a liver cytosolic isoform of acetaldehyde dehydrogenase and is involved in the major pathway of alcohol metabolism along with alcohol dehydrogenase . ALDH1A1 is also known as retinal dehydrogenase 1 and is involved in retinol metabolism, converting retinol to retinoic acid . Recent studies suggest that control of retinoid signaling through ALDH1A1 may influence hematopoietic stem cell differentiation . There has been recent interest in ALDH1 isoforms as predictive biomarkers in disease. Several studies have suggested that ALDH1A1 is a potential marker for cancer stem cells and chemoresistance in several tumor types, such as melanoma , lung cancer , glioblastoma . Synonyms: ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1, |
Immunogen | Recombinant protein of human ALDH1A1 |
Other Names | AL1A1|aldc|aldh-e1|aldh1|aldh11|pumb1|raldh1|ALDH1A1|ALDC|ALDH-E1|ALDH1|ALDH11|PUMB1|RALDH1|Ahd2|Aldh1|Aldh2|GGADHR|ALDDH|Ahd-2|Aldh1a2|E1|Raldh1 |
Gene, Accession # | Gene ID: 216,11668,24188 |
Catalog # | ABIN1683354 |
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Order / More Info | Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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