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| Product Name | MESDC1, 1-362aa, Human, His tag, E.coli |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT . Mesoderm development candidate 1, also known as MESDC1, belongs to the MESD family. It is a 362 amino acid protein encoded by a gene that maps to human chromosome 15q25.1. MESDC1 acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6). MESDC1 is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. Recombinant human MESDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Mesoderm development candidate 1, MGC99595 |
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| Gene, Accession, CAS # | NP 072088 |
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| Catalog # | ATGP2657 |
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| Order / More Info | MESDC1, 1-362aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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