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| Product Name | Recombinant Human G-protein coupled receptor 161 |
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| Description | 1-28aa; Partial. MW: 30.4kD. Purity >90% as determined by SDS-PAGE. Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is roved from p |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [G-protein coupled receptor RE2] |
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| Gene, Accession, CAS # | GPR161, Gene ID: 23432, Accession: NP_001254538.1 |
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| Catalog # | MBS717231 |
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| Order / More Info | Recombinant Human G-protein coupled receptor 161 from MYBIOSOURCE INC. |
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| Product Specific References | Isolation of cDNA coding for G-protein coupled receptor RE2.Warren C.N., Aronstam R.S., Sharma S.V. Identification of a novel G-protein coupled receptor expressed in distinct brain regions and a defined olfactory zone.Raming K., Konzelmann S., Breer H.Recept. Channels 6:141-151(1998) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine |
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