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| Product Name | Bone Morphogenetic Protein 7 (BMP7) (Active) protein (His tag) |
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| Description | Synonyms: BMP-7, OP-1, osteogenic protein 1 The bone morphogenetic proteins are a family of secreted signalling molecules that can induce ectopic bone growth. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Bone morphogenetic protein 7 (BMP-7), also known as osteogenic protein 1 (OP1), is a widely expressed TGFb superfamily member with important functions during embryogenesis, in the adult, and in disease (Chen et al., 2004, Kishigami and Mishina 2005). BMP-7 plays a role in a variety of organ systems. It promotes new bone formation and nephron development (Sampath et al., 1992, Kazama et al., 2008), inhibits the branching of prostate epithelium (Grishina et al., 2005), and antagonizes epithelialmesenchymal transition (Zeisberg et al., 2003, Yu et al., 2009). In pathological conditions, BMP7 inhibits tumor growth and metastasis (Buijs et al., 2007), ameliorates fibrotic damage in nephritis (Zeisberg et al., 2003), and promotes neuroregeneration following brain ischemia (Chou et al., 2006). |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Cell Culture (CC),Western Blotting (WB) |
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| Other Names | bmp-7|bmp7|op-1|BMP7|zgc:153025|OP-1|OP1|BMP-7|fb83f09|wu:fb83f09 |
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| Gene, Accession, CAS # | Gene ID: 655 |
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| Catalog # | ABIN1019690 |
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| Order / More Info | Bone Morphogenetic Protein 7 (BMP7) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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