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Product Name | Bone Morphogenetic Protein 2 (BMP2) (Active) protein |
Description | BMPs (Bone Morphogenetic Proteins) belong to the TGF beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Alternative Names: BMP-2 protein, BMP-2, BMP 2, BMP-2A protein, BMP-2 protein, BMP2, BMP 2 protein, Bone Morphogenetic protein 2 protein |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | BMP-2|xBMP-2|xbmp2|BMP2|bmp2a|BDA2|BMP2A|AI467020|Bmp2a|2610024H22Rik|AL117858|AW546137|BB189135|BMPR-2|BMPR-II|BMPRII|BRK-3|Gm20272 |
Gene, Accession, CAS # | Gene ID: 650 |
Catalog # | ABIN935232 |
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Order / More Info | Bone Morphogenetic Protein 2 (BMP2) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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