| 产品详情 |
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| Product Name | Human CellExp™ Fas Ligand/FasL, human recombinant |
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| Description | Fas ligand also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its binding with its receptor induces apoptosis. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Mature human Fas Ligand consists of a 179 amino acid (aa) extracellular domain (ECD), a 22 aa transmembrane segment, and a 80 aa cytoplasmic domain. Within the ECD, human Fas Ligand shares 81% and 78% aa sequence identity with mouse and rat Fas Ligand, respectively. Apoptosis triggered by Fas-Fas ligand binding plays a fundamental role in the regulation of the immune system. Its functions include T-cell homeosta |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | FASLG, ALPS1B, APT1LG1, CD178, CD95-L, CD95L, FASL, TNFSF6, Fas ligand |
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| Gene, Accession, CAS # | FASLG, Gene ID: 356, Accession: P48023 |
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| Catalog # | 7443-10 |
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| Order / More Info | Human CellExp™ Fas Ligand/FasL, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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