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Product Name | Human CellExp™ EGFRvIII, human recombinant |
Description | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. The type III EGF deletion-mutant receptor (EGFRvIII) is the most common mutation and was first identified in primary human glioblastoma tumors; EGFR gene amplification is correlated with the structural rearrangement of the gene. The EGFRvIII gene has an in-frame delet |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
Gene, Accession, CAS # | EGFR, Gene ID: 1956, Accession: P00533 |
Catalog # | P1082-10 |
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Order / More Info | Human CellExp™ EGFRvIII, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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