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| Product Name | IRGM, 23-181aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 20.1 kDa (180aa). Purity >90% by SDS-PAGE. Immunity-related GTPase family M protein, also known as IRGM, is required for clearance of acute protozoan and bacterial infections. This protein functions in innate immune response probably through regulation of autophagy. It may regulate proinflammatory cytokine production and prevent endotoxemia upon infection and may also play a role in macrophages adhesion and motility. Recombinant human IRGM protein, fused to His-tag at N-terminus, was express |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Immunity-related GTPase family M protein; IFI1; IRGM1; LRG-47; LRG47; MGC149263; MGC149264] |
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| Gene, Accession, CAS # | IRGM, Gene ID: 345611, Accession: NP_001139277 |
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| Catalog # | MBS205425 |
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| Order / More Info | IRGM, 23-181aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Singh S.B., et al. (2006) Science. 313:1438-1441; Parkes M., et al. (2007) Nat. Genet. 39:830-832; |
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