| 产品详情 |
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| Product Name | Irinotecan HCl |
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| Description | MW: 623.14. Irinotecan is a topoisomerase 1 inhibitor, which prevents DNA from unwinding. Chemically it is a semisynthetic analogue of the natural alkaloid camptothecin. It is activated by hydrolysis to SN-38 which is then inactivated by glucuronidation by UGT1A1. This inactivation eventually leads to inhibition of both DNA replication and transcription (1, 2). |
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| Size | 50 mg, 250 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate; CPT11; Camptothecin 11 |
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| Gene, Accession, CAS # | CAS: 100286-90-6 |
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| Catalog # | abx076771 |
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| Price | |
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| Order / More Info | Irinotecan HCl from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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