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| Product Name | LY6/PLAUR Domain Containing 3 (LYPD3) (AA 31-286) protein (His tag) |
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| Description | Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.Alternative Names: Ly6/PLAUR Domain-Containing Protein 3, GPI-Anchored Metastasis-Associated Protein C4.4A Homolog, Matrigel-Induced Gene C4 Protein, MIG-C4, LYPD3, C4.4A |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LYPD3|MGC139913|C4.4A|2310061G07Rik|C4.4a |
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| Gene, Accession, CAS # | Gene ID: 27076 |
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| Catalog # | ABIN1096170 |
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| Order / More Info | LY6/PLAUR Domain Containing 3 (LYPD3) (AA 31-286) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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