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| Product Name | CDC7 Recombinant protein |
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| Description | MW: ~94 kDa. Recombinant full-length human CDC7 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: CDC7 is a cell division cycle protein that is critical for the G1/S transition and initiation of DNA replication during the cell division cycle. Overexpression of CDC7 gene product may be associated with neoplastic transformation for some tumors. Inhibition of CDC7 in cancer cells impairs progression through S phase, inducing a p53-ind |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [CDC7L1; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238] |
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| Gene, Accession, CAS # | CDC7, Gene ID: 8317, Accession: NP_003494.1 |
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| Catalog # | MBS515101 |
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| Order / More Info | CDC7 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Montagnoli, A. et al: Targeting cell division cycle 7 kinase: a new approach for cancer therapy. Clin Cancer Res. 2010 Sep 15;16(18):4503-8. 2. Chuang, L C. et al: Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry. Mol Cell. 2009 Jul 31;35(2):206-16. |
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