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| Product Name | Recombinant Mouse Metalloproteinase inhibitor 1 (Timp1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 36.2kDa. Full Length of Mature Protein: 25-205aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates th by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.1 Publication |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Collagenase inhibitor 16C8 fibroblastErythroid-potentiating activity; EPATPA-S1TPA-induced protein; Tissue inhibitor of metalloproteinases 1; TIMP-1 |
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| Gene, Accession, CAS # | Timp1, UniProt: P12032 |
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| Catalog # | RPC22123 |
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| Order / More Info | Recombinant Mouse Metalloproteinase inhibitor 1 (Timp1) from BIOMATIK |
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| Product Specific References | n/a |
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