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Product Name | Murine IL-36 alpha (160a.a.) protein |
Description | Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases.IL-36D, IL-36G, and IL-36H (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptorfamily members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36D is mainly found in skin and lymphoid tissues, but also in fetal brain,trachea, stomach and intestine. It is expressed by monocytes, B and T cells. Notably, IL-36 alpha is the only novel IL-1 familymember expressed on T-cells. Recombinant murine interleukin-36 alpha contains 160 amino acids residues which is a single nonglycosylatedpolypeptide. Specifically, mouse IL-36D shares 83 % a.a. sequence identity with rat IL-36D, 54-60 % with human,rabbit, equine and bovine IL-36D. MW: 18.0 kDa. Purity > 95 % by SDS-PAGE and HPLC analyses |
Size | 2 ug, 10 ug, 1 mg, 100 ug, 250 ug, 500 ug |
Concentration | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, 5 % trehalose. |
Applications | HPLC, SDS-PAGE |
Other Names | Murine Interleukin-36 alpha protein |
Gene, Accession, CAS # | n/a |
Catalog # | orb107764 |
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Order / More Info | Murine IL-36 alpha (160a.a.) protein from BIORBYT LTD. |
Product Specific References | n/a |
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