| 产品详情 |
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| Product Name | SR8278 |
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| Description | An antagonist of REV-ERBα (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112; stimulates the expression of the REV-ERBα target genes G6Pase and PEPCK in liver cells; used to elucidate the role of REV-ERBα in regulating glucagon secretion in pancreatic alpha cells |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1426385-65-0 biochemical receptor antagonist nuclear gene regulation signal transduction intracellular signaling metabolism circadian clock metabolic syndrome carbohydrate research diabetes REV-ERBα GSK 4112 REVERBα GSK4112 SR8278 G6Pase PEPCK liver cell glucagon secretion pancreatic pancreas alpha glucose 6-phosphatase phosphoenolpyruvate carboxykinase |
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| Gene, Accession, CAS # | CAS: 1254944-66-5 |
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| Catalog # | 17000-5 |
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| Order / More Info | SR8278 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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