| 产品详情 |
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| Product Name | SR 3677 |
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| Description | A potent inhibitor of ROCK-II and ROCK-I in enzyme and cell-based assays (IC50s = 3 and 56 nM, respectively); efficacious at inhibiting myosin light chain phosphorylation and increasing aqueous humor outflow in porcine eyes in an ex vivo model of glaucoma treatment |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1072959-67-1 biochemicals inhibitors kinases protein kinases ophthalmology intracellular signaling ATP-competitive Rho-kinase potent ROCK I II RockI RockII enzyme cell assay inhibit Akt3 Clk1 Clk2 Clk4 Lats2 SR3677 myosin light chain phosphorylation aqueous humor outflow porcine eye ex vivo model glaucoma treatment |
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| Gene, Accession, CAS # | CAS: 1072959-67-1 |
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| Catalog # | 16708-5 |
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| Price | |
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| Order / More Info | SR 3677 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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