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| Product Name | 1-Methylnicotinamide (chloride) |
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| Description | Purity >95%. Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(aminocarbonyl)-1-methyl-pyridinium, monochloride, N1-Methylnicotinamide chloride, Nicotinamide methochloride, Trigonellamide chloride |
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| Gene, Accession, CAS # | CAS: 1005-24-9 |
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| Catalog # | LS-H5896 |
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| Price | |
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| Order / More Info | 1-Methylnicotinamide (chloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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