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| Product Name | Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial |
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| Description | 24-495. Partial, provide the complete extracellular domain of the Isoform 2. MW: 56.5 kDa. Purity >90% as determined by SDS-PAGE. Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Muscle-specific tyrosine-protein kinase receptor] |
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| Gene, Accession, CAS # | MUSK, Gene ID: 4593, Accession: NP_001159752.1 |
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| Catalog # | MBS7053479 |
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| Order / More Info | Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial from MYBIOSOURCE INC. |
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| Product Specific References | The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.Bergamin E., Hallock P.T., Burden S.J., Hubbard S.R.Mol. Cell 39:100-109(2010) |
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