产品名称 |
LRG1, Recombinant, Human, aa36-347, His-Tag (Leucine-Rich Alpha-2-Glycoprotein, LRG1, HMFT1766, LRG) from UNITED STATES BIOLOGICAL |
产品详情 |
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Product Name | LRG1, Recombinant, Human, aa36-347, His-Tag (Leucine-Rich Alpha-2-Glycoprotein, LRG1, HMFT1766, LRG) |
Description | Purity ~95% (SDS-PAGE). LRG1, also known as leucine-rich alpha-2-glycoprotein, is a member of leucine-rich repeat (LRR) family. It is neutrophilic expressed during granulocyte differentiation. It has been shown to be involved in protein- protein interaction, signal transduction, and cell adhesion and development. It binds directly to the TGF-beta accessory receptor endoglin, which, in the presence of TGF-beta1, results in promotion of the pro-angiogenic Smad1/5/8 signaling pathway. It promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation. It is a key physiological regulator of dendrite complexity of hippocampal pyramidal neurons. It physically interacts with TrkB and attenuates BDNF signaling. Recombinant human LRG1, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa36-347 of human LRG1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular W |
Size | 20ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | Accession: NP_443204 |
Catalog # | 396899 |
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Order / More Info | LRG1, Recombinant, Human, aa36-347, His-Tag (Leucine-Rich Alpha-2-Glycoprotein, LRG1, HMFT1766, LRG) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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