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Product Name | Interleukin 5, Human, BioAssay™ ELISA Kit (IL-5, Interleukin-5, B Cell Differentiation Factor I, T-cell Replacing Factor, TRF) |
Description | Intended Use: This Human Interleukin 5 ELISA Kit is to be used for the in vitro quantitative determination of human Interleukin 5 (IL-5) concentrations in serum, plasma, cell culture medium and urine. This kit is intended for research use only and not to be used for diagnostic purposes. It is intended for research use only and is not to be used in diagnostic or therapeutic procedures. Human IL-5 is a 135 amino acid (aa) polypeptide with a predicted mass of 12.5kD. It is secreted by a restricted number of mesenchymal cell types. In its native state, mature IL-5 is synthesized as a 115aa, highly glycosylated 22kD monomer that forms a 40-50kD disulfide-linked homodimer. Although the content of carbohydrate is high, carbohydrate is not needed for bioactivity. Monomeric IL-5 has no activity; a homodimer is required for function. This is in contrast to the receptor-related cytokines IL-3 and GM-CSF, which exist only as monomers. Just as one IL-3 and GM-CSF monomer binds to one receptor, one |
Size | 96 tests |
Concentration | n/a |
Applications | ELISA |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | I8427-04 |
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Order / More Info | Interleukin 5, Human, BioAssay™ ELISA Kit (IL-5, Interleukin-5, B Cell Differentiation Factor I, T-cell Replacing Factor, TRF) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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