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Product Name | BAFF Receptor, Control Peptide (BAFF-R, BR3, BLyS Receptor 3) |
Description | Blocking peptide for B0003-68. Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4 (1- 4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Two receptors, TACI and BCMA, for BAFF were originally identified (5). A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3 (6,7). Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-FeB and c-jun N-terminal kinase (4-6). Applications: Suitable for use in ELISA and Western Blot. |
Size | 50ug |
Concentration | n/a |
Applications | ELISA WB |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | B0003-68A |
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Order / More Info | BAFF Receptor, Control Peptide (BAFF-R, BR3, BLyS Receptor 3) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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