| 产品详情 |
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| Product Name | SRT-3025 hydrochloride |
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| Description | MW: 606.2, Purity ≥98% by HPLC. SRT-3025 is a potent and selective Sirt1 activator. It inhibits RANKL-induced osteoclast differentiation, fusion and resorptive capacity without affecting osteoclast survival. SRT-3025 inhibits RANKL-induced osteoclastogenesis in bone marrow-derived macrophages (BMMs) by activating AMPK and deacetylating RelA/p65 lysine 310, critical for activation of the NF-κB signaling pathway. |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 5-(3-methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride, SRT3025 HCl |
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| Gene, Accession, CAS # | CAS: 2070015-26-6 |
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| Catalog # | B2376-25 |
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| Order / More Info | SRT-3025 hydrochloride from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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