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| Product Name | Recombinant Human Replication protein A 70 kDa DNA-binding subunit |
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| Description | 2-616. Full length. . MW: 84kD. Purity >90% as determined by SDS-PAGE. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellula |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding protein] |
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| Gene, Accession, CAS # | RPA1, Gene ID: 6117, Accession: NP_002936.1 |
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| Catalog # | MBS967200 |
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| Order / More Info | Recombinant Human Replication protein A 70 kDa DNA-binding subunit from MYBIOSOURCE INC. |
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| Product Specific References | Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication.Erdile L.F., Heyer W.-D., Kolodner R., Kelly T.J.J. Biol. Chem. 266:12090-12098(1991) Type I human complement C2 deficiency. A 28-base pair gene deletion causes skipping of exon 6 during RNA splicing.Erdile L.F., Heyer W.-D., Kolodner R., Kelly T.J.J. Biol. Chem. 268:2268-2268(1993) Complete sequencing and characterization of 21,243 full |
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