| 产品详情 |
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| Product Name | Recombinant Human Replication factor C subunit 1 (RFC1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 11.8kDa. Partial: 402-492aa. N-terminal 6xHis-tagged. Homo sapiens (Human). The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Activator 1 140 kDa subunit |
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| Gene, Accession, CAS # | RFC1, UniProt: P35251 |
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| Catalog # | RPC24920 |
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| Price | |
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| Order / More Info | Recombinant Human Replication factor C subunit 1 (RFC1), partial from BIOMATIK |
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| Product Specific References | n/a |
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