| 产品详情 |
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| Antigenic Specificity | SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (aa 84-309), (PDZ Domain), (SH3 Domain) |
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| Clone | S23b-6 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | alkaline phosphatase (AP) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Immunoprecipitation (IP),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina. Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimer's disease.Cellular Localization: Cytoplasm, Cell Junction | Synapse | postsynaptic cell membrane | postsynaptic density, cell projection | growth cone |
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| Immunogen | Fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (SH3 and multiple ankyrin repeat domains protein 2) |
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| Other Names | shank2|MGC122482|SHANK2|AUTS17|CORTBP1|CTTNBP1|ProSAP1|SHANK|SPANK-3|CortBP1|Spank-3|auts17|cortbp1|cttnbp1|prosap1|spank-3|mKIAA1022 |
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| Gene, Accession # | Gene ID: 22941,210274,171093 |
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| Catalog # | ABIN2484030 |
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| Price | |
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| Order / More Info | SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (aa 84-309), (PDZ Domain), (SH3 Domain) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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